Advancing MRI-Guided Radiation Therapy for Gynecologic Cancers
At Brigham and Women’s Hospital, DFF is supporting investigators who are pioneering MRI-guided radiation therapy as a non-invasive alternative to traditional brachytherapy for gynecologic cancers. Through the MR-SMART clinical trial, this innovative approach enables real-time tumor visualization during treatment; improving…
Improving Diagnostic Techniques to Distinguish Uterine Sarcomas from Leiomyomas
At Dana-Farber Cancer Institute, DFF is supporting efforts to validate the first practical, MRI-based tool designed to distinguish malignant uterine sarcomas from benign fibroids before surgery. By supporting large-scale validation with expert radiologists and national patient partnerships, this work aims…
Exploring Genes and Pathways Transforming Benign Uterine Leiomyoma to Malignant Leiomyosarcoma
At Northwestern University Feinberg School of Medicine, DFF is catalyzing groundbreaking research to uncover the molecular pathways that drive the transformation of benign uterine fibroids into aggressive leiomyosarcoma. This work has identified new diagnostic biomarkers, revealed novel disease mechanisms, and…
Advancing Education to Improve Outcomes for Women with Malignant Uterine Fibroids
At Brigham and Women’s Hospital, DFF supports the development of innovative, patient-centered educational resources to address one of the most urgent gaps in women’s health: distinguishing rare malignant uterine tumors from common benign fibroids. By funding new digital tools and…